Emily, a product manager at a video gaming company, had recently been tapped to lead a new AI workgroup. Incorporating machine learning into their game development was a major strategic direction for the firm and she felt honored to spearhead such a crucial initiative. But colleagues from other departments were slow to respond to her emails, often missing meetings or deprioritizing AI-related tasks. She told me, “My boss keeps saying to give it time. That new projects take a while to gain traction.” When Emily did manage to gather her stakeholders, she sensed a lack of urgency and buy-in. “They see this workgroup as just another burden,” Emily said. “I know we’d move faster if there was more visible support from my boss and the rest of the leadership team.”
HBO Almost Cut the Industry Season Finale’s Most Shocking Scene
In the volatile universe of Industry, all debts must be paid.
In Sunday night’s season three finale, “Infinite Largesse,” no one understood that better than Rishi (Sagar Radia), whose gambling addiction finally caught up with him.
(Spoiler alert: The following includes spoilers for Industry’s third season finale.)
Rishi, for the uninitiated, spent much of the last season falling deeper and deeper into debt. As the finale concluded, Industry gave him one of the revelation-packed episode’s biggest twists when his bookie, Vinay, showed up and killed Rishi’s wife over £600,000 in unpaid gambling debts. It was the kind of gut-wrenching moment that has made HBO Sunday-night appointment TV—and, according to cocreators Mickey Down and Konrad Kay, HBO almost nixed it.
“There was a conversation about Rishi’s wife’s death, which HBO balked at,” Kay says.
Early on, as Down and Kay outlined season 3, they knew they wanted to do a Rishi episode, which fans were treated to in episode 4, “White Mischief.” Shot as a kind of homage to Uncut Gems, it was there viewers got a taste of the real Rishi, who, it turned out, was a gambler with a dangerous appetite for risk, drugs, and women.
“We first wrote it with a bow at the end of it,” Down says. “He gets out of his position, he’s saved by the market. He then gets his wife to pay back his debt and then he makes his phone call, doubling down on it. We really didn’t think we were going to return to this. We thought, OK, are we going to show the repercussions of this in some way?”
But HBO saw the potential in it and advised the creators to return to Rishi later in the season. “They said, we have to show what happens to him.” It presented a unique challenge for Down and Kay. “How can you actually show that there are consequences to your actions in this world and that you can’t just talk your way out of everything?”
When they landed on the idea that it would be Diana, Rishi’s wife, who ultimately paid for Rishi’s financial misfortunes, HBO pushed back. But Down and Kay knew better.
“At the script stage, HBO wanted to get rid of it,” Kay says. “Then we said, look, let us shoot it and show it to you. And we shot it and cut it and showed it to them. And they were like, ‘This is fantastic.’ We got very few notes. What you see in the season finale is pretty close to the first cut of that episode.”
Originally, the scene played out differently. “We were like, what if the guy shot Rishi?” Down continues. “Personally, and practically, we wanted Rishi in season four. But it’s more heartbreaking that his wife, who is a victim of all of this, is the person that bears the brunt. And those are consequences that he then has to live with.”
But by killing Diana, Down and Kay felt it would provide the perfect setup for next season. (HBO renewed Industry after WIRED’s interview with the showrunners.)
Their instincts proved right. As the finale aired on Sunday, reaction online was swift, with fans posting Succession-esque responses to the show’s many turns of fortune.
“Industry is so good because they just keep moving forward. Mickey and Konrad are completely unafraid to put characters on paths they can’t easily undo for the sake of plot convenience. this is peak storytelling,” @lesliezye posted on X following the finale.
Added @cinnaMENA, “From Rishi’s sad bachelor pad scene to Yasmin’s country house breakdown I—I have emotional whiplash.”
For Down and Kay, it was all about elevating the storyline into new heights. “That core is shaken when something sort of seismic happens,” Down says of his scheming characters. “And your wife being shot in front of you to settle the gambling debt is a seismic thing, which means that Rishi in season four will be a totally different character than he was in season three and before.”
Cardiac amyloidosis — What is amyloid and how does it affect the heart
Martha Grogan, M.D., Cardiovascular Medicine, Mayo Clinic: Hi, I’m Dr. Martha Grogan, and I’m a cardiologist at the Mayo Clinic, and today I would like to discuss with you some information concerning a condition called cardiac amyloidosis. And if you’re watching this, it’s probably because either you or someone close to you has been diagnosed with cardiac amyloidosis. And this is a very scary thing, but you really cannot beat any disease until you understand it. So my goal today is to review what every patient needs to know about cardiac amyloidosis. So first of all, what is amyloid? How does it affect your heart? I’ll explain the tests that you need to evaluate your heart–basically, what do all those numbers mean? And what are your treatment options if you have cardiac amyloidosis?
Well, amyloid is a disease of what we call protein misfolding. So there are normally soluble proteins in your bloodstream that for a variety of reasons become insoluble, and they deposit abnormally in the tissues and organs throughout your body. They can deposit in the kidney, the intestinal tract, the carpal tunnel ligaments, and the heart and other structures.
So why does that happen? Well, there are three main kinds of amyloid that actually can affect the heart, and there are over 20 proteins that can form amyloid, but only really three that affect the heart. So first we’ll talk about those. The first type is called AL amyloid, and the A stands for amyloid and L stands for light chain type. And this is an immunoglobulin, a protein that is normally made to fight infection. But you have abnormal cells in your bone marrow that are making too much of these light chains, and they form to then form amyloid protein that deposits in the organ and tissues of your body. So in this case, the main problem are the cells in the bone marrow that are making too many light chains. And the AL type of amyloid often affects multiple organs. It can affect the heart, the kidneys, the gastrointestinal tract, and the nervous system.
The other main type of amyloid that can deposit in the heart is what’s called transthyretin amyloid, and it’s named because the protein that we all actually have in our body. It transports thyroid hormone and retinol, which is vitamin A. So the letters TTR are for transports, thyroid hormone and retinol. So we abbreviate that as TTR. And there are two types of TTR amyloid that can affect your heart. The first type is what’s called hereditary or sometimes called familial amyloid, and in that type, an individual has a mutation which makes the protein abnormal. So the TTR protein has a different structure that makes it unstable, and it tends to form this amyloid fibral that then gets deposited throughout your body. The hereditary form of TTR amyloid most commonly affects the nerves and can cause neuropathy, or it affects the heart or sometimes both. The other type of TTR amyloid is called wild type. It previously was also called senile, but a lot of our patients are a little bit happier to be called the wild type rather than senile. Another name for it is age-related TTR amyloid. And this is really a mysterious situation in which the protein is actually normal. It’s normal protein that we all have. There is no mutation or abnormal molecular structure that we can find, but for reasons that are mysterious, this protein becomes misfolded and forms the amyloid substance that deposits in the heart. And in this type of amyloid, usually only the heart and ligaments of the carpal tunnel are involved, and it almost exclusively affects men usually over the age of 60. So what happens when the heart is involved with amyloid is really the same in all three of these types, whether it’s AL amyloid or whether it’s the hereditary TTR or if it’s the wild type TTR. But the diseases themselves have different building blocks of the protein, and they actually behave very differently.
So now I’ll show you some images about how does this actually affect your heart? What those amyloid do and how does it affect your heart function? So your heart is about the size of your fist, and it’s in the left side of your chest, and it’s divided into upper and lower chambers. So you have two upper chambers. Here’s the right atrium and the left atrium, and these are called atria. They’re primarily collecting chambers. They don’t really do too much pumping. And the lower chambers of your heart are called the ventricles, and they’re the ones that really pump the blood around your body. So the right ventricle pumps blood to the lungs, where it gets oxygen, and the left ventricle is the main pumping chamber of your heart that pumps blood to the rest of your body. So when blood comes back from your lungs after it’s gotten oxygen, it comes into this upper chamber on the left side, the left atrium. Then it goes through a valve. And you have four valves in your heart. They just open and close to make the blood continue to flow in the right direction. Then blood goes into the left ventricle, and when the left ventricle squeezes, it then sends blood out through this aortic valve and into the aorta, which is the main blood vessel of your body, so that blood can travel up here to your brain and then on down to the rest of your body, to your kidneys, your legs, and all of the various organs to deliver oxygen, the fuel that we all need.
So what happens in amyloid heart disease is that the walls of the heart, particularly the lower chambers, have become much thicker than they should be. So here we see that both the walls of the right ventricle and of the left ventricle are much thicker, and that’s due to the process of amyloidosis. But why does that really happen? It’s really very interesting. It’s not that you have more muscle in your heart, it’s that you have this substance called amyloidosis. So if we were able to look at heart muscle under the microscope, if we took some normal heart muscle and looked at it under a microscope, we would see that there are nice individual heart muscle cells, and they’re arranged in an orderly fashion, and they’re packed pretty tightly together. And interestingly, each one of these cells actually contracts, and then as they shorten, that makes the heart squeeze and pump blood around your body. But in amyloid, the walls of the heart are thicker than they should be. But you can see it’s not because there’s more muscle cells. And in fact, the muscle cells are disrupted, and that’s because of the abnormal protein from amyloidosis that deposits in between the heart muscle cells. So here we see what we call the amyloid fibrals that form from abnormal misfolded proteins, and then they get in between the heart cells and cause dysfunction. So your heart should normally be quite elastic. It should be flexible. And when the heart relaxes, your heart stretches out, and then it squeezes and contracts. But when the heart is infiltrated with amyloidosis, it’s much stiffer than normal. So the main problem for most patients with cardiac amyloidosis is not necessarily that their heart is weak, it’s that the walls of the heart are too thick and they’re too inflexible. So it’s hard for the heart to fill with blood, and when you can’t get as much blood into your heart, then you don’t have as much blood that you can send around to your body. So that leads to a condition called heart failure, when there’s not enough blood to meet the demands of your body and when pressure, then, can build up into your heart and cause a syndrome caused congestive heart failure. So, again, we see here’s what it would look like with normal heart, and this is the heart muscle that’s been infiltrated by amyloid.
So I hope that these pictures have been of some use for you, explaining a little bit about cardiac amyloidosis and how it happens. And in another segment, we’ll talk about what are the tests that we use to diagnose cardiac amyloidosis and what are the treatment options?
Source link
‘It was a really lonely time’: Alison Moyet and Dave Stewart on making Is This Love? | Culture
Alison Moyet, singer, songwriter
I’d left school at 16 and kept getting sacked from jobs in shops because I was so easily distracted. I was singing in punk bands and my only ambition was to headline at the Hope & Anchor in London. Then Vince Clarke answered my advert in Melody Maker and suddenly I was a pop star with Yazoo.
After Vince split the band up, I was subject to a record company injunction that meant I couldn’t record for a year. My lawyer stopped taking my calls, I became agoraphobic and I couldn’t even listen to music because it hurt too much. Eventually, I got back to working and made the Alf album but I felt so disconnected I gave up trying to take control and was happy to be led.
For my second album, Raindancing, my new manager suggested I record in Los Angeles with Jimmy Iovine, who’d produced U2, John Lennon, Bruce Springsteen’s The River and so on. His track record was eye-watering. But I went out there on my own and it was a really lonely time. Often, Jimmy wasn’t there. I’d be put in rooms with engineers and big session musicians, then suddenly have to get out of the studio because a bigger act was coming in.
When Dave Stewart from Eurythmics came in, it was a big relief. He was warm, eccentric, excitable, daft and full of energy, everything I liked. Jimmy put us together to write a song, which wasn’t a normal way of writing for me – I’d never done it before – but I wasn’t intimidated because I liked Dave a lot. We were together for the shortest time but enough for him to come up with a chord progression and a melody idea. I took off to the room I was renting and wrote the lyrics for Is This Love? that night.
The lyrics are basically me being in quite a dark place but trying to subvert it, in a very GCSE English kind of way. The first line – “In a fleeting moment of a restless day, driven to a distraction, I was captured by the game” – is a sort of mix-up of the game of love and more personal stuff going on in my life. It’s become my most popular song. Forty years on, I sing it with a more Twin Peaks vibe now, but there’s an innocent joy to it – which I think came from Dave’s energy – and a universal simplicity. You don’t have to struggle to get the meaning. You can just sing along.
Dave Stewart, songwriter
I became friends with Jimmy when Eurythmics first toured America. We had the same sense of humour and I ended up living in his house. People would come over and I was always being asked to produce records or write songs, but not in the way of having six people trying to write a hit – it was more happenstance. I hadn’t written songs at all until I was involved in a huge motorway pile-up in Germany and punctured my lung. In the hospital, coming round from a very painful operation, I had an epiphany, and embraced the idea of a vortex of chaos as a way of life and a means of songwriting.
When Alison came in Jimmy just said: “Hey, this is Alison Moyet. You should get in a room together and write a song.” Before I knew it, having never met, we were sat in a room with nothing in it. I had an acoustic guitar and Is This Love? just tumbled out between us really quickly. The words are all great but Alison came up with one of my favourite lyrics: “Let our bodies be twisted but never our minds.”
The original hit version has an electronic feel, because it was the 80s. To tell the truth, I prefer the version she does live now: the slower, moodier, atmospheric version with strings suits the words much better.
Is This Love? has always been credited to Alison and “Jean Guiot”. I used a pseudonym because I didn’t want to dilute the songs written by Annie Lennox and me for Eurythmics and it wasn’t important to me to announce to the world: “Whoo hoo, I wrote this!” I actually used three or four pseudonyms back then. Some years later, my management company were looking at my statements and said: “We’re confused. Who are all these people?” I had to admit that they were all me.
Source link
We want you to join us with long cardigans!
We want you to join us in our monthly series. Which, by the way, has been running for many years! But of course it wouldn’t mean anything without you. So we hope that you will make a little effort to send in your photos and a few sentences. And we will let you shine on the 15th!
We want you to join us with The Good Buy/Good-Bye Book.
Shelbee of Shelbee On the Edge and myself started this series after we had hosted The Bad Buy Book for a year. Now we are ready for a new challenge! Every 15th of the month we show our Good Buy or Good-Bye item. And we want you to join!
You can choose yourself whether you want to show a Good Buy (which is an item you are really exited about) or a Good-Bye ( which is an item you are going to say good bye to). We will keep buying a Bad Buy from now and then, you know, it was so cheap, you were in a hurry and really wanted(needed) to buy something etc. But of course we also have those purchases that can make us so very happy. A piece of clothing that you have had for years and that you also wear a lot. Or something you bought on a holiday, and every time you wear it you get that holiday feeling back. Every month you can choose which item you want to send in. A Good Buy or a Good-Bye. We will provide a theme for each month!
Send us a photo of your favourite, or not so favourite long cardigans!
You can send either a Good Buy, a long cardigan that you are thrilled about, or a long cardigan that you are going to say Good-Bye to. Write a few lines why it is a Good Buy or a Good-Bye or send in both! If you want to be featured on both our blogs, please sent in different outfit photos. You have the time until the 10th to send us your photos! Mail to: info@nancysfashionstyle.com or shelbeeontheedge@gmail.com
We will feature you on October 15th on both our blogs and social media. We are looking forward to see your contribution!
Have a great day,
Shelbee & Nancy
Source link
Key revelations emerge in Coast Guard’s Titan submersible hearing
Two weeks of public testimony concluded Friday in the U.S. Coast Guard’s investigation to establish what caused the Titan submersible to implode during a deep ocean dive last year, killing all five on board.
Its findings will be issued in a report that may include what the panel believes caused the incident; whether there was any act of misconduct, negligence or violation of law; and safety recommendations that could prevent future calamities involving submersibles.
The hearing in South Carolina included former employees and executives of OceanGate, the Washington state-based operator of the Titan, some speaking publicly for the first time, as well as industry experts who sought to piece together the culture of the company, its business plan and the run-up to the fatal dive.
In June 2023, the Titan was almost two hours into its descent to view the Titanic wreckage in the North Atlantic Ocean off Canada when the vessel lost contact with its support ship, setting off a frantic search. The public’s fascination only deepened with reports that “banging noises” were detected from the search site and amid concerns over how long its passengers could sustain themselves in a cramped tube running out of oxygen.
Those on board were OceanGate CEO Stockton Rush, 61, who was piloting the Titan; deep sea explorer Paul-Henri Nargeolet, 77, who was experienced in visiting the Titanic wreck site; British tycoon Hamish Harding, 58; and Pakistani businessman Shahzada Dawood, 48, and his son, Suleman, 19.
Almost immediately, OceanGate came under heavy scrutiny as a result of the disaster, in part because it involved civilian passengers paying $250,000 apiece to go on the expedition, but also because fatal incidents involving submersibles — of which a handful are capable of diving as deep as the Titanic — are nearly unheard of.
Here are key revelations that emerged from the Coast Guard’s hearing:
Debris images helped to confirm implosion
At the outset of the hearing, the Coast Guard released photos and video of the Titan’s tail cone resting on the bottom of the Atlantic near the Titanic’s bow.
While officials concluded in the initial investigation that the Titan was likely involved in a “catastrophic implosion” because the craft couldn’t handle the deep-sea water pressure, the discovery of the debris was what made them confident no one survived, they said.
The Coast Guard also revealed one of the last messages the Titan sent to its support ship before losing contact: “All good here.”
Cost issues may have compromised safety, ex-employees claim
David Lochridge, the former marine operations director of OceanGate, testified that Rush was more concerned about profits and cost-cutting measures than in building a viable submersible.
“The whole idea behind the company was to make money,” said Lochridge, who joined OceanGate in early 2016 and was fired from his role after about two years. “There was very little in the way of science.”
Lochridge would go on to be locked in a legal battle with OceanGate, claiming he was fired because he complained about quality control.
Another former engineering executive, Tony Nissen, said he voiced concerns to Rush after the Titan’s original hull — made out of experimental carbon fiber, which has not been proven to repeatedly withstand deep-sea pressures — was compromised after it was struck by lightning during a test mission in 2018. Nissen said he was fired after he refused to sign off on another test mission the following year and had even told Rush, “I’m not getting in it,” referring to the Titan.
Meanwhile, OceanGate’s former director of administration, Amber Bay, who joined the company in early 2019, testified that there were instances when the business couldn’t meet payroll, so Rush had to dip into his own money.
“He increased his investment by making a deposit, and we were able to meet payroll,” she said, adding that the financial situation was so pinched that employees were also asked to defer their paychecks.
OSHA accused of failing to review safety concerns in timely manner
In January 2018, following his firing at OceanGate, Lochridge said he filed a quality inspection report regarding the building of the Titan with the Occupational Safety and Health Administration, the federal agency that oversees workplace safety.
Upon Lochridge’s termination, OceanGate filed a lawsuit alleging breach of contract, claiming he violated terms of his contractual employment by discussing confidential information with other employees and OSHA representatives.
But instead of OSHA pressing ahead with his claims, he said the representatives only dragged their feet — allowing OceanGate to go unchecked as it designed and built the Titan.
“I believe that if OSHA had attempted to investigate the seriousness of the concerns I raised on multiple occasions, this tragedy may have been prevented,” Lochridge said.
An OSHA spokesperson said in a response to NBC News that the agency did forward his safety allegations to the Coast Guard, which has the jurisdiction to investigate such claims. The agency said it could review only his claims of employment retaliation, and that “the investigation followed the normal process and timeline for a retaliation case.”
Once Lochridge and OceanGate agreed to settle their litigation in late 2018, OSHA ended its investigation “pursuant to the terms of the parties’ agreement,” the spokesperson said.
Titan never inspected by industry organization
Roy Thomas, an engineer for the American Bureau of Shipping, testified that OceanGate never contacted the organization, which advises and verifies whether a marine vessel complies with industry standards.
Thomas said the choice of the main material for the hull, carbon fiber, which has long been used within the aerospace industry, is “susceptible to fatigue failure” in deep-sea pressure settings. Submersible hulls typically use titanium; carbon fiber is also costlier.
Thomas added that the organization would never have classified the Titan based on the materials used. The Coast Guard also noted at the start of the hearing that the Titan never underwent an independent review, which is standard practice in the industry.
Titan malfunctioned just days before doomed final dive
The Titan suffered more than 100 equipment issues in the two years before the June 2023 implosion, including losing its forward dome during a test dive in 2021 and a mechanical failure that same year during an expedition to the Titanic. That trip had to be aborted.
The Titan also malfunctioned days before the implosion, marine scientist Steven Ross testified.
Rush was piloting a trip with Ross and others on board. At one point, an issue with the Titan’s buoyancy caused the platform to shift and the passengers were left to “tumble about,” Ross said. No one was hurt, but it took an hour to get out of the water during such a distressing incident, he added.
“One passenger was hanging upside down,” Ross said. “The others managed to wedge themselves into the bow end cap.”
Exact cause of implosion may be ‘indeterminate’
Expert testimony from Bart Kemper of Kemper Engineering Services gave preliminary findings for what may have caused the disaster.
Among the possibilities, he said, are breakage of the carbon fiber hull, a manufacturing failure related to the hull or an issue with the acrylic window.
Ultimately, “the root cause for the implosion is indeterminate at this time,” Kemper said.
Earlier in the hearing, OceanGate co-founder Guillermo Söhnlein, who left the company a decade before the Titan disaster but continued to champion Rush’s efforts, said a cause for the implosion may never be known.
“I don’t know who made what decision when and based on what information,” he told the hearing panel. “And honestly, I don’t know if any of us will ever know this, despite all of your team’s investigative efforts.”
OceanGate CEO had cavalier attitude: ‘No one is dying’
Witnesses who knew Rush painted a picture of a businessman who strove for innovation in creating a new type of submersible, but also refused to slow down.
Matthew McCoy, a former OceanGate operations technician, testified about a “tense” meeting with Rush in 2017 about what the CEO said he would do if he came under regulatory scrutiny at a U.S. port.
“If the Coast Guard became a problem, then he would buy himself a congressman and make it go away,” McCoy said, adding that he resigned soon after.
William Kohnen, the CEO and founder of submersible maker Hydrospace Group, said he spoke to Rush in 2018 about the direction of OceanGate as peers in the industry took notice of what he was doing.
Rush “said the usual response that ‘it takes too long,’” Kohnen testified about getting OceanGate’s submersible classified by the industry. “‘It’s too expensive and they don’t know about this technology. I don’t have time to explain my technology.’”
That same year, Lochridge had confronted Rush about his safety concerns before he was fired. In a transcript of the conversation made public by the Coast Guard as part of the hearing, Rush denied he was going to put anyone at risk with the Titan.
“Everything I’ve done on this project is people telling me it won’t work. You can’t do that,” Rush said.
“I can come up with 50 reasons why we have to call it off and we fail as a company,” he added. “I’m not dying. No one [is] dying under my watch period.”
Source link
Dr Reddy’s completes acquisition of Haleon’s global NRT portfolio | Company News
“We would like to inform you that the acquisition has now been completed, and the company has made a payment of upfront cash consideration of GBP 458 million,” the Hyderabad-based drug major said in a regulatory filing.
Click here to connect with us on WhatsApp
DRL’s Swiss subsidiary completed the acquisition through the purchase of shares of Northstar Switzerland SARL, a Haleon group company.
“As part of this acquisition, Northstar Switzerland, along with its wholly-owned subsidiaries North Star OpCo Limited (United Kingdom) and North Star Sweden AB (Sweden), are now wholly-owned step-down subsidiaries of the company with effect from September 30, 2024,” the company said.
The acquired portfolio consists of Nicotinell, a global leader in the NRT category, with an extensive footprint in over 30 countries spanning Europe, Asia, and Latin America. The portfolio includes all formats, such as lozenges, patches, and gum, as well as pipeline products, in all applicable global markets outside of the US.
First Published: Sep 30 2024 | 6:57 PM IST
Source link
Asus ProArt PZ13 Review: A Cheaper Surface Pro
Microsoft’s latest Surface Pro is the standard-bearer for detachable 2-in-1 Copilot+ PCs. But as I noted in my review at the time, it suffers from several issues—most notably a sky-high price of $1,950 as it was configured for our tests. No matter what you think about the detachable keyboard concept, this device comes with an awfully hard price to swallow.
Enter Asus with a suspiciously similar concept, albeit considerably cheaper. I wouldn’t quite call this the Wish version of the Surface Pro, but at $1,100, the ProArt PZ13 may at least take some of the sting out of the cash outlay should you venture down this road.
To trim the price, Asus has made its fair share of sacrifices. Certain elements remain the same, including a 13-inch touchscreen, 16 GB of RAM, and a magnetically attached keyboard, which comes included with your purchase. Otherwise, the ProArt comes across as a slightly different animal. It starts with the stripped-down CPU: The ProArt uses a Qualcomm Snapdragon X Plus X1P42100 instead of the more capable Elite that dominated the first wave of Copilot+ PCs. The aspect ratio and resolution of the two screens are slightly different—2,880 x 1,920 pixels on the Surface versus 2,880 x 1,800 on the ProArt—and although the ProArt screen isn’t nearly as vibrant and bright, I had no complaints with it through several days of use.
Surprisingly, there are a couple of upgrades on tap from Asus over what comes on the Surface Pro. Instead of Microsoft’s 512-GB SSD, Asus packs in a 1-TB drive by default. It also enhances the two USB-C 4.0 ports—one required for charging on the ProArt, unlike the Surface Pro—with a full-size SD card slot. Oddly, the card slot and one of the USB-C ports are hidden under a rigid plastic flap that’s difficult to open and does little more than get in the way.
Source link
My Favorite Boots With Chunky Heels To Buy Now
You know what cooler weather means! Boots! That’s right, today I’m sharing My Favorite Boots With Chunky Heels To Buy Now! I’ve found some amazing styles that will have you stepping out in confidence, whether you’re out for a casual day or a night on the town. From platform boots to ankle booties, there’s something here for every occasion. Let’s check out these beauties!
What are the advantages of a chunky heel?
I love me a good chunky heel! The biggest advantage is comfort. Unlike skinny stilettos, chunky heels offer support and stability, making them easier to walk in for longer periods of time. Plus, they give you that extra height without the wobbles! Another bonus is versatility—chunky heels look great with everything from jeans to dresses, and they can easily take you from day to night. Finally, they’re on-trend but still timeless, so you can rock them season after season without worrying about going out of style. Ha! That’s what I call a win-win!
This article might contain affiliate links. If you decide to make a purchase after clicking on one of the shopping links, I may receive a commission. As a participant of the Amazon Associates program, I earn from qualifying purchases.
Vince Camuto is a brand I love, and I always run to at the Nordstrom sale. The Cristen Knee High Boot are all about simplicity and elegance. I know they are fancy, but they give me a Western vibe. The heel is 3 inches high, so I’d wear them on occasions that didn’t include a ton of walking. No, I’m not doing the boot-scooting boogie in these, lol. I love that they are leather, so you can keep them looking good for a long time. They run true to size and come in wide calf sizes, so no worries about fit!
Ankle Boots With Chunky Heels To Buy Now
I don’t wear black shoes too often, thanks to a cousin who made fun of my “large” feet. He used to tell me that I needed to back up to a door to knock on it. However, I already have the Blondo® Sinner Booties (TTS) in tan, and I liked them so much that I also bought them in black. These will fill a void that is missing from my fall wardrobe.
My boot of choice is a camel/beige ankle boot. I love the neutral color that goes with everything, and I find myself wearing them all the time. The Soffit Tara Leather Booties (TTS) were one of my go-to booties last year. I find that they run true to size and have a thick, chunky heel which makes them very stable. I paired them with bootcut jeans, most of the time, but I also like them with a maxi dress!
Chunky doesn’t have to mean short, lol. This is the perfect pair for all you Gurls who love a chic and polished look! The chunky block heel adds height while keeping things super comfy. I’m loving the pointed toe, which gives this bootie a little extra edge. These boots could be worn in a variety of ways—you can pair them with everything from mini dresses to your favorite skinny jeans! Available in black leather and a gorgeous suede, they’ll fit right into your fall wardrobe. These boots will totally “elevate” your outfits in more ways than one!
My Favorite Boots With Chunky Heels To Buy Now
These chunky heel Chelsea Boots (TTS) are perfect for adding a little edge to your fall outfits. They are super comfortable and have a chunky sole that gives them a modern vibe. You can wear this outfit for a casual day out, whether it’s hitting the pumpkin patch or grabbing coffee with friends.
How many ways could you wear this pair of boots? About a zillion! If you’re looking for chunky boots that stand out, this is your winner! The decorative side zippers make these boots pop, and easy to put on. The sole is sturdy, —perfect for a day of shopping or lunch with friends. They look great with leggings or even a long cardigan!
I love a beautiful pair of brown boots. These are Chelsea (named after a really hip part of London) and are the perfect blend of style and practicality! The chunky heel gives you some height while the waterproof design keeps your feet dry—ideal for those unpredictable fall days. They’re easy to slip on and off, and the leather finish adds a sleek look. Pair them with a trench coat and skinny jeans for a polished, everyday vibe. Available in black and brown, these boots are a closet staple for the cooler months!
I know I’m showing a lot of black boots, but talk about a wardrobe essentials, these would go with everything. Imagine these paired with skinny jeans or a cute fall dress. They come in classic black and tan, giving you some fab options for your wardrobe. They do tend to run a bit small, so you might consider sizing up at least a half size. Plus, that makes comfy socks an option.
My Favorite Boots With Chunky Heels To Buy Now
For all my Gurls who love a little edge, these Dr. Martens boots are for you! The platform heel gives you serious height while staying sturdy with that iconic chunky sole. I love how they add a bold vibe to any outfit, whether you’re rocking a cute skirt or a pair of distressed jeans. The leather is durable, and the lace-up design means you can customize the fit. Doc Martens never go out of style, and no, you’re not too old to wear them!
These ankle boots are giving me all the fall feels! The chunky heel is on-trend and comfy, and I love how the Chelsea style makes them easy to pair with just about anything. You can wear these with a cute dress or even some leggings for a laid-back look. They come in a range of colors, including classic black and bright white, so they’ll fit perfectly into your wardrobe. These are a very affordable option!
These remind me of the pricier versions I shared above. If you like your chunky heel a bit higher and your price a little lower, this is for you! The chunky heel adds height while keeping you stable—no teetering here! They come in black, tan, and white, and although you can’t see it, there’s a zipper on the other side, so getting them on and off should be simple.
My Favorite Boots With Chunky Heels To Buy Now
These black chunky heel boots are giving me life, Gurls! The block heel is super sturdy and they have a pointed toe that adds a little extra sass. Like the others, a zipper makes them easy to slip on and off. These boots are perfect for anyone looking to add some on-trend style to their closet. The come in two different black versions, brown and browner, lol. Another affordable option if you’re on a budget!
Now, here’s a boot that’s both trendy and practical! The tan sole gives it a unique twist, and the chunky heel adds some serious style points. These boots look great with a pair of jeans or even a casual dress. The extra inches you get from the heel will make your legs look long, and who doesn’t love that? Plus, they’re super comfy for everyday wear. Gurls, if you’re looking for something a little different, this is the boot for you!
So there you have it, Gurls—My Favorite Boots With Chunky Heels To Buy Now! Whether you need something casual, chic, or a little bit bold, these boots are going to take your fall wardrobe to the next level. Happy shopping!
Each time you SHARE my posts on PINTEREST, INSTAGRAM, YOUTUBE, AND FACEBOOK, it not only helps other ladies who might be style-challenged find my blog but also strengthens our community. Furthermore, I appreciate every one of you and consider you a friend.
Are You One Of The GURLS?
You will get a daily email reminder from me, letting you know when a new blog post has gone live. Additionally, a “special” email may occasionally hit your inbox, so be sure to watch for those!
To GOD Goes The Glory!
Verse Of The Day
1 Timothy 4:12 NIV
12 Don’t let anyone look down on you because you are young, but set an example for the believers in speech, in conduct, in love, in faith and in purity.
50 Is Not Old partners with affiliate platforms where commission may be earned based on clicks and or purchases, and I would love it if you decided to use the links above. Affiliate Links help bloggers like me fund the free content we provide on our blogs. As an Amazon Influencer, I earn from qualifying purchases. Some products might be gifted from brands.
Related
India-specific big cancer database goes live
A public-private national project in India has introduced what could be the country’s first comprehensive cancer multi-omics database fifteen years after its founding.
The Indian Cancer Genome Atlas (ICGA) focuses on studying cancer biology specific to the Indian population to create datasets that can be utilised in developing personalised treatment protocols
Based on a media release, the open-access ICGA portal initially includes clinically annotated data on DNA, RNA, and protein profiles of breast cancer patients, along with their treatment histories and outcomes. By next year, the available data will be expanded from the current 50 patients to over 500.
“This data is freely accessible to the global research community under India’s PRIDE guidelines, which promote ethical sharing and collaboration in cancer research,” a press statement noted.
The portal was built based on the cBioPortal for Cancer Genomics platform developed by the Memorial Sloan Kettering Cancer Center in New York.
THE LARGER TREND
Health and medical researchers in India have long relied on databases from global sources. “Historically, cancer treatments in India have been based on Western data sets. However, cancers in Indian patients can differ significantly at the molecular level,” the ICGA said.
Two years ago, India’s peak body for biomedical research, the Indian Council of Medical Research, started building datasets representing Indian diversity. These datasets, for one, will underpin the development and integration of AI technologies in healthcare.
In 2023, India recorded over two million new cases of cancer – the third highest in the world. Late detection and poor intervention are reportedly driving this trend.
Digital technologies have been identified as one solution to address India’s growing cancer problem. The Koita Centre for Digital Oncology established by the government-backed National Cancer Grid is one of those centres established to promote the digitalisation of cancer care in the country.
ON THE RECORD
“Cancer touches all of us, and the need for more effective, personalised treatments – especially tailored to the unique genetic and environmental factors in India – is urgent. This portal will empower researchers with crucial data to advance customised cancer research for better treatment outcomes,” Dr Anand Deshpande, a non-executive director of ICGA, commented.
Source link
BBC Strictly Come Dancing's Karen Hauer supported by co-star's famous fiancee after Paul Merson survival
During week two of the competition, former footballer Paul and pro dancer Karen got the studio bouncing
Source link
China’s missile intercept test a message for India? Here’s what we know | External Affairs Defence Security News
China recently conducted a missile intercept test near the Indian border, which state news agency Xinhua reported only on August 29, with experts reportedly interpreting it as a clear message of deterrence for India even as both nations intensify diplomatic efforts to resolve their long-standing territorial dispute along the Line of Actual Control (LAC).
The precise location of the test, which was part of a live-fire exercise featuring surface-to-air missile operations on the Karakoram Plateau, was not disclosed, and its timing remains unclear. However, Chinese state media reported the missile intercept test on the same day that India and China held their 31st meeting on border affairs in Beijing, where they agreed to strengthen dialogue and maintain peace along their border.
What happened during China’s missile intercept test?
During the test, a subsonic cruise missile was successfully intercepted at an altitude of 5,300 metres for the first time, said the Xinhua report, adding that the test demonstrated that the Chinese interceptor missile remained effective even in challenging conditions.
There has been a flurry of recent bilateral political and diplomatic talks between New Delhi and Beijing, including the 30th and 31st meetings of the Working Mechanism for Consultation & Coordination on India-China Border Affairs (WMCC) on July 31 and August 29.
These discussions were followed by a meeting between National Security Advisor Ajit Doval and Chinese Foreign Minister Wang Yi on the sidelines of a BRICS summit in St Petersburg on September 12.
What message is China trying to send?
Lin Minwang, deputy director of Fudan University’s Centre for South Asian Studies in Shanghai, told the South China Morning Post that amid the ongoing tensions with India, the PLA has been testing weapons and equipment in China’s border plateau region since 2020. Lin added that China’s recent missile intercept test aligns with this practice.
According to Lin, the missile intercept test carries a “certain deterrent massage”. Lin’s take was that China’s stance is that to avoid war, it must “first possess the capability to fight”.
Meanwhile, Song Zhongping, a Chinese military commentator, told the South China Morning Post that the recent test could be seen as a “guarantee of strength”, which China thinks will back the diplomatic negotiations to break the deadlock at the LAC.
According to Song, the belief in Beijing could be that “negotiations without such a guarantee of strength” are unlikely to yield results.
How is India likely to view China’s test?
Speaking to the South China Morning Post, Rajeev Ranjan Chaturvedy, an associate professor at Nalanda University’s School of Historical Studies in India, explained that the recent test could raise concerns in New Delhi.
Chaturvedy noted that the test had “significant implications for regional security dynamics” and indicated that China was “actively enhancing its military capabilities”.
Chaturvedy also warned that the timing of the test, coming amid ongoing discussions between the two nations, could prompt India to reassess its defence priorities. He added that the focus on establishing a stronger deterrent force could “trigger an arms race in the region”.
India, for its part, could feel compelled to accelerate the development of its own military capabilities, including hypersonic missiles, long-range air-launched cruise missiles, and nuclear ballistic missile submarines, Chaturvedy suggested.
First Published: Sep 30 2024 | 4:55 PM IST
Source link